Exploring the Mechanism of Baicalin Intervention in Breast Cancer Based on MicroRNA Microarrays and Bioinformatics Strategies.
Anqi GeLifang LiuXian'guang DengJun LuoYanghua XuPublished in: Evidence-based complementary and alternative medicine : eCAM (2021)
Baicalin inhibits the proliferation of breast cancer cells. It may achieve antitumor effects through regulating microRNAs so as to affect the DNA replication (such as cellular response to DNA damage stimulus and DNA binding), RNA transcription (such as regulation of transcription, DNA-templated, transcription from RNA polymerase II promoter, and transcription factor binding), protein synthesis (such as mRNA binding, Golgi apparatus, and protein complex), endocytosis, pathways in cancer, p53 signaling pathway, and so on.
Keyphrases
- transcription factor
- dna binding
- signaling pathway
- dna damage
- breast cancer cells
- randomized controlled trial
- papillary thyroid
- oxidative stress
- binding protein
- genome wide identification
- pi k akt
- epithelial mesenchymal transition
- circulating tumor
- nucleic acid
- squamous cell
- amino acid
- squamous cell carcinoma
- childhood cancer
- young adults
- endoplasmic reticulum
- protein protein
- cell proliferation