TACC3 expression as a prognostic factor in aggressive types of adult T-cell leukemia/lymphoma patients.

Mayuko MoritsuboHiroaki MiyoshiKotaro MatsudaNoriaki YoshidaKazutaka NakashimaEriko YanagidaKyohei YamadaMai TakeuchiTakaharu SuzukiHiroko MutaTakeshi UmenoTakuya FurutaMasao SetoKoichi Ohshima

Published in: International journal of laboratory hematology (2020)

Certain drugs that inhibit TACC3-overexpressing neoplastic cells are used clinically. Further studies might highlight a key role for TACC3 in the oncogenesis and progression of ATLL.

Keyphrases

prognostic factors
end stage renal disease
induced apoptosis
ejection fraction
newly diagnosed
chronic kidney disease
poor prognosis
acute myeloid leukemia
bone marrow
peritoneal dialysis
cell cycle arrest
signaling pathway
cell proliferation
oxidative stress
endoplasmic reticulum stress
binding protein
pi k akt