EGCG Suppresses Adipogenesis and Promotes Browning of 3T3-L1 Cells by Inhibiting Notch1 Expression.
Yinghao WangChunfeng LiWenyuan PengJun ShengCheng-Ting ZiXiaoyun WuPublished in: Molecules (Basel, Switzerland) (2024)
In this study, molecular docking and in vitro cell experiments were used to explore the possible mechanism of EGCG to improve obesity by inhibiting Notch1.
Keyphrases
- molecular docking
- signaling pathway
- induced apoptosis
- high fat diet induced
- molecular dynamics simulations
- poor prognosis
- cell proliferation
- insulin resistance
- metabolic syndrome
- single cell
- cell cycle arrest
- weight gain
- oxidative stress
- skeletal muscle
- cell death
- physical activity
- mesenchymal stem cells
- body mass index
- adipose tissue