Associations between TLR4 Polymorphisms and Open Angle Glaucoma: A Meta-Analysis.

Zhongjing LinShouyue HuangJun SunBing Xie Yisheng Zhong

Published in: BioMed research international (2019)

The meta-analysis highlighted that certain mutations of some TLR4 polymorphisms might increase the susceptibility of OAG. However, TLR4 polymorphisms are still far from being candidate genetic biomarkers for OAG. Additional researches involving larger scale epidemiological studies are warranted to validate our results.

Keyphrases

toll like receptor
inflammatory response
systematic review
immune response
case control
nuclear factor
genome wide
randomized controlled trial
gene expression
dna methylation