Effects of vitamin C supplementation on gout risk: results from the Physicians' Health Study II trial.
Stephen P JuraschekJ Michael GazianoRobert J GlynnNatalya GomelskayaVadim Y BubesJulie E BuringRobert H ShmerlingHoward D SessoPublished in: The American journal of clinical nutrition (2022)
Vitamin C modestly reduced the risk of new gout diagnoses in middle-aged male physicians. Additional research is needed to determine the effects of higher doses of vitamin C supplementation on serum urate and gout flares in adults with established gout.The Physicians' Health Study II is registered at clinicaltrials.gov (identifier: NCT00270647).