Osteoporosis in inflammatory bowel disease.

Patients with inflammatory bowel disease (IBD) are at increased risk for osteoporosis and fracture. This is considered to be relevant to IBD-related risk factors, including intestinal inflammation, low nutrient status and the use of corticosteroids, in addition to general risk factors, such as age, gender and BMI et al. A recent meta-analysis suggests that bisphosphonate is effective and safe for the treatment of low bone mineral density and reduce risk of vertebral fractures in patients with IBD. With recent advances in medical treatment for IBD, the number of elderly IBD patients is expected to increase in future. Prevention and treatment of osteoporosis associated with IBD is essential for improving QOL of patients with IBD.