Analysis of bone erosions in rheumatoid arthritis using HR-pQCT: Development of a measurement algorithm and assessment of longitudinal changes.
Kazuteru ShiraishiKo ChibaKounosuke WatanabeNozomi OkiNaoki IwamotoShoken AmanoAkihiko YonekuraMasato TomitaMasataka UetaniAtsushi KawakamiMakoto OsakiPublished in: PloS one (2022)
The measurement algorithm developed for bone erosions at MCP joints showed good reproducibility. Both progression and repair of bone erosions were observed in patients with RA even after 12 months of appropriate treatment. Our algorithm may be useful to investigate the etiology of RA and assess drug efficacy.
Keyphrases
- rheumatoid arthritis
- bone mineral density
- machine learning
- deep learning
- disease activity
- soft tissue
- bone loss
- ankylosing spondylitis
- neural network
- interstitial lung disease
- body composition
- emergency department
- systemic lupus erythematosus
- systemic sclerosis
- cross sectional
- combination therapy
- smoking cessation
- idiopathic pulmonary fibrosis