Delayed Supplementation Strategy of Extracellular Vesicles from Adipose-Derived Mesenchymal Stromal Cells with Improved Proregenerative Efficiency in a Fat Transplantation Model.
Shan MouYuan LiDi SunMuran ZhouJialun LiLifeng ChenShaokai LiuJie YangPeng XiaoJing TongZhenxing WangJiaming SunPublished in: Stem cells international (2022)
Delayed injection of ADSC-EVs promotes fat graft volume retention by stimulating angiogenesis. These findings suggest that delayed supplementation might be a more effective strategy for the application of MSC-EVs in tissue regeneration.