Acute-on-Chronic Liver Failure in Pregnant Patients with Chronic Hepatitis B: A Retrospective Observational Case Series Study.
Shiwei WangHaofeng XiongChangling LuoHong ZhaoYing FanTing ZhangLili WangQi WangWen XiePublished in: Gastroenterology research and practice (2020)
Asthenia, anorexia, and jaundice during mid-late pregnancy should be immediately investigated. Before and during the pregnancy, hepatologists or obstetricians should actively screen pregnant women with CHB for HBV DNA status and alanine aminotransferase levels. Reactivation of HBV replication in pregnant women with CHB may lead to ACLF, especially in multiparous women. Once ACLF is diagnosed, antiviral therapy should be considered as soon as possible to protect maternal and fetal health.
Keyphrases
- liver failure
- hepatitis b virus
- pregnancy outcomes
- pregnant women
- preterm birth
- public health
- healthcare
- mental health
- high throughput
- single molecule
- circulating tumor
- polycystic ovary syndrome
- adipose tissue
- birth weight
- health information
- cross sectional
- mesenchymal stem cells
- type diabetes
- intensive care unit
- atomic force microscopy
- physical activity
- mass spectrometry
- cell free
- gestational age
- smoking cessation
- liver fibrosis
- extracorporeal membrane oxygenation
- mechanical ventilation
- social media