Login / Signup

Dengue NS1 interaction with lipids alters its pathogenic effects on monocyte derived macrophages.

Shashika DayarathnaBhagya SenadheeraChandima JeewandaraMadushika DissanayakeFarha BaryGraham S OggGathsaurie Neelika Malavige
Published in: Journal of biomedical science (2024)
As RPLP2 is important in DENV replication, regulating cellular stress responses and immune responses and IL-10 is associated with severe disease, it would be important to further explore how differential expression of RPLP2 and IL-10 could lead to disease pathogenesis based on NS1 and lipid interactions.
Keyphrases
  • dengue virus
  • zika virus
  • immune response
  • dendritic cells
  • aedes aegypti
  • fatty acid
  • early onset
  • endothelial cells
  • toll like receptor
  • inflammatory response