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Diet-induced iron deficiency in rats impacts small intestinal calcium and phosphate absorption.

Evans O AsowataOluwatobi OlusanyaKaoutar AbaakilHavovi ChichgerSurjit K S SraiRobert J UnwinJoanne Marks
Published in: Acta physiologica (Oxford, England) (2021)
We propose that iron deficiency alters calcium and phosphate transport in the duodenum. This occurs via changes to the paracellular pathway, whereby upregulation of claudin 2 increases calcium absorption and upregulation of claudin 3 inhibits phosphate absorption.
Keyphrases
  • iron deficiency
  • poor prognosis
  • cell proliferation
  • signaling pathway
  • long non coding rna