Diet-induced iron deficiency in rats impacts small intestinal calcium and phosphate absorption.

Evans O AsowataOluwatobi OlusanyaKaoutar AbaakilHavovi ChichgerSurjit K S SraiRobert J UnwinJoanne Marks

Published in: Acta physiologica (Oxford, England) (2021)

We propose that iron deficiency alters calcium and phosphate transport in the duodenum. This occurs via changes to the paracellular pathway, whereby upregulation of claudin 2 increases calcium absorption and upregulation of claudin 3 inhibits phosphate absorption.

Keyphrases

iron deficiency
poor prognosis
cell proliferation
signaling pathway
long non coding rna