Dietary cholesterol drives fatty liver-associated liver cancer by modulating gut microbiota and metabolites.

Xiang ZhangOlabisi Oluwabukola CokerEagle Sh ChuKaili FuHarry Cheuk Hay LauYi-Xiang WangAnthony W H ChanHong WeiXiaoyong YangJoseph J Y SungJun Yu

Published in: Gut (2020)

Dietary cholesterol drives NAFLD-HCC formation by inducing alteration of gut microbiota and metabolites in mice. Cholesterol inhibitory therapy and gut microbiota manipulation may be effective strategies for NAFLD-HCC prevention.

Keyphrases

low density lipoprotein
ms ms
signaling pathway
stem cells
type diabetes
high fat diet induced
mesenchymal stem cells
adipose tissue
insulin resistance
bone marrow