Jun Yu

ResearcherID ORCID

Publication Activity (10 Years)

Years Active: 2016-2023
Publications (10 Years): 87

Top Venues

Oncogene

Gut

Cancers

The Journal of pathology

Chinese University of Hong Kong

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Chinese University of Hong Kong Apr 1o 2011

Hong Kong

Professor :: Dept of Medicine and Therapeutics

Publications

Wing Sum Shin, Fuda Xie, Bonan Chen, Jun Yu, Kwok-Wai Lo, Gary M K Tse, Ka Fai To, Wei Kang
Exploring the Microbiome in Gastric Cancer: Assessing Potential Implications and Contextualizing Microorganisms beyond H. pylori and Epstein-Barr Virus. Cancers 15 (20) (2023)
Huan Yan, Jing-Ling Zhang, Kam-Tong Leung, Kwok-Wai Lo, Jun Yu, Ka-Fai To, Wei Kang
An Update of G-Protein-Coupled Receptor Signaling and Its Deregulation in Gastric Carcinogenesis. Cancers 15 (3) (2023)
Yaqi Gao, Pingping Xu, Danfeng Sun, Yi Jiang, Xiao-Lin Lin, Ting Han, Jun Yu, Chunquan Sheng, Hao-Yan Chen, Jie Hong, Ying-Xuan Chen, Xiu-Ying Xiao, Jing-Yuan Fang
Faecalibacterium prausnitzii abrogates intestinal toxicity and promotes tumor immunity to increase the efficacy of dual CTLA-4 and PD-1 checkpoint blockade. Cancer research (2023)
Yali Liu, Harry Cheuk Hay Lau, Jun Yu
Microbial metabolites in colorectal tumorigenesis and cancer therapy. Gut microbes 15 (1) (2023)
Yali Liu, Harry Cheuk Hay Lau, Jun Yu
Microbial metabolites in colorectal tumorigenesis and cancer therapy. Gut microbes 15 (1) (2023)
Wing Sum Shin, Fuda Xie, Bonan Chen, Peiyao Yu, Jun Yu, Ka Fai To, Wei Kang
Updated Epidemiology of Gastric Cancer in Asia: Decreased Incidence but Still a Big Challenge. Cancers 15 (9) (2023)
Wing Sum Shin, Fuda Xie, Bonan Chen, Peiyao Yu, Jun Yu, Ka Fai To, Wei Kang
Updated Epidemiology of Gastric Cancer in Asia: Decreased Incidence but Still a Big Challenge. Cancers 15 (9) (2023)
Yanqiang Ding, Liuyang Zhao, Guoping Wang, Yu Shi, Gang Guo, Changan Liu, Zigui Chen, Olabisi Oluwabukola Coker, Junjun She, Jun Yu
PacBio sequencing of human fecal samples uncovers the DNA methylation landscape of 22 673 gut phages. Nucleic acids research (2023)
Jinglin Zhang, Bonan Chen, Yifei Wang, Xiaoli Liu, Huan Yan, Kit Yee Wong, Aden Ka Yin Chan, Alvin Hk Cheung, Chit Chow, Dazhi Xu, Shouyu Wang, Bing Huang, Li Liang, Huixing Ke, Chi Chun Wong, William K K Wu, Alfred Sl Cheng, Jun Yu, Kwok-Wai Lo, Ka Fai To, Wei Kang
The E2F1-HOXB9/PBX2-CDK6 axis drives gastric tumorigenesis and serves as a therapeutic target in gastric cancer. The Journal of pathology (2023)
Alvin Ho-Kwan Cheung, Kit-Yee Wong, Xiaoli Liu, Fenfen Ji, Chris Ho-Lam Hui, Yihan Zhang, Johnny Sheung-Him Kwan, Bonan Chen, Yujuan Dong, Raymond Wai-Ming Lung, Jun Yu, Kwok-Wai Lo, Chi Chun Wong, Wei Kang, Ka-Fai To
MLK4 promotes glucose metabolism in lung adenocarcinoma through CREB-mediated activation of phosphoenolpyruvate carboxykinase and is regulated by KLF5. Oncogenesis 12 (1) (2023)
Huan Yan, Jing-Ling Zhang, Kam-Tong Leung, Kwok-Wai Lo, Jun Yu, Ka-Fai To, Wei Kang
An Update of G-Protein-Coupled Receptor Signaling and Its Deregulation in Gastric Carcinogenesis. Cancers 15 (3) (2023)
Jessie Qiaoyi Liang, Yao Zeng, Effie Yin Tung Lau, Yuting Sun, Yao Huang, Tingyu Zhou, Zhilu Xu, Jun Yu, Siew Chien Ng, Francis Ka Leung Chan
A Probiotic Formula for Modulation of Colorectal Cancer Risk via Reducing CRC-Associated Bacteria. Cells 12 (9) (2023)
Yinnan Chen, Quanpeng Qiu, Junjun She, Jun Yu
Extrachromosomal circular DNA in colorectal cancer: biogenesis, function and potential as therapeutic target. Oncogene (2023)
Yali Liu, Harry Cheuk Hay Lau, Jun Yu
Microbial metabolites in colorectal tumorigenesis and cancer therapy. Gut microbes 15 (1) (2023)
Rashid Nok-Shun Lui, Sunny-Hei Wong, Nik Sheng Ding, Masau Sekiguchi, Jun Yu, Tiing-Leong Ang, Khay-Guan Yeoh, Han-Mo Chiu, Joseph Jao Yiu Sung
Is this the end of colonoscopy screening for colorectal cancer? An Asia-Pacific perspective. Journal of gastroenterology and hepatology (2023)
Yali Liu, Harry Cheuk Hay Lau, Jun Yu
Microbial metabolites in colorectal tumorigenesis and cancer therapy. Gut microbes 15 (1) (2023)
Jessie Qiaoyi Liang, Yao Zeng, Effie Yin Tung Lau, Yuting Sun, Yao Huang, Tingyu Zhou, Zhilu Xu, Jun Yu, Siew Chien Ng, Francis Ka Leung Chan
A Probiotic Formula for Modulation of Colorectal Cancer Risk via Reducing CRC-Associated Bacteria. Cells 12 (9) (2023)
Zhenjie Yang, Shanshan Gao, Chi Chun Wong, Weixin Liu, Huarong Chen, Haiyun Shang, Zoe Yuet Wu, Lixia Xu, Xiang Zhang, Nathalie Wong, Ming Kuang, Jun Yu
TUBB4B is a novel therapeutic target in nonalcoholic fatty liver disease-associated hepatocellular carcinoma. The Journal of pathology (2023)
Zhenjie Yang, Shanshan Gao, Chi Chun Wong, Weixin Liu, Huarong Chen, Haiyun Shang, Zoe Yuet Wu, Lixia Xu, Xiang Zhang, Nathalie Wong, Ming Kuang, Jun Yu
TUBB4B is a novel therapeutic target in non-alcoholic fatty liver disease-associated hepatocellular carcinoma. The Journal of pathology (2023)
Yinnan Chen, Quanpeng Qiu, Junjun She, Jun Yu
Extrachromosomal circular DNA in colorectal cancer: biogenesis, function and potential as therapeutic target. Oncogene 42 (13) (2023)
Wenchao Wei, Chi Chun Wong, Zhong-Jun Jia, Weixin Liu, Changan Liu, Fenfen Ji, Yasi Pan, Feixue Wang, Guoping Wang, Liuyang Zhao, Eagle S H Chu, Xiang Zhang, Joseph Jao Yiu Sung, Jun Yu
Parabacteroides distasonis uses dietary inulin to suppress NASH via its metabolite pentadecanoic acid. Nature microbiology (2023)
Jessie Qiaoyi Liang, Yao Zeng, Effie Yin Tung Lau, Yuting Sun, Yao Huang, Tingyu Zhou, Zhilu Xu, Jun Yu, Siew Chien Ng, Francis Ka Leung Chan
A Probiotic Formula for Modulation of Colorectal Cancer Risk via Reducing CRC-Associated Bacteria. Cells 12 (9) (2023)
Winnie Fong, Qing Li, Fenfen Ji, Wei Liang, Harry Cheuk Hay Lau, Xing Kang, Weixin Liu, Kenneth Kin-Wah To, Zhong Zuo, Xiao-Xing Li, Xiang Zhang, Joseph Jao Yiu Sung, Jun Yu
Lactobacillus gallinarum -derived metabolites boost anti-PD1 efficacy in colorectal cancer by inhibiting regulatory T cells through modulating IDO1/Kyn/AHR axis. Gut (2023)
Yongzhan Nie, Xianchun Gao, Xiqiang Cai, Zhen Wu, Jessie Qiaoyi Liang, Guobing Xu, Na Liu, Peng Gao, Jingyu Deng, Hongzhi Xu, Zhanlong Shen, Changqi Cao, Fenrong Chen, Nannan Zhang, Yongxi Song, Mingjun Sun, Chengyin Liu, Guangpeng Zhou, Weili Han, Jianhua Dou, Huahong Xie, Liping Yao, Zhiguo Liu, Gang Ji, Xin Wang, Qingchuan Zhao, Lei Shang, Daiming Fan, Xiaoliang Han, Jianlin Ren, Han Liang, Zhenning Wang, Jinhai Wang, Qi Wu, Jun Yu, Kaichun Wu, null null
Combining methylated SEPTIN9 and RNF180 plasma markers for diagnosis and early detection of gastric cancer. Cancer communications (London, England) (2023)
Chuangen Li, Harry Cheuk Hay Lau, Xiang Zhang, Jun Yu
Mouse Models for Application in Colorectal Cancer: Understanding the Pathogenesis and Relevance to the Human Condition. Biomedicines 10 (7) (2022)
Olabisi Oluwabukola Coker, Changan Liu, William Ka Kei Wu, Sunny Hei Wong, Wei Jia, Joseph J Y Sung, Jun Yu
Altered gut metabolites and microbiota interactions are implicated in colorectal carcinogenesis and can be non-invasive diagnostic biomarkers. Microbiome 10 (1) (2022)
Changan Liu, Siu-Kin Ng, Yanqiang Ding, Yufeng Lin, Weixin Liu, Sunny Hei Wong, Joseph Jao-Yiu Sung, Jun Yu
Meta-analysis of mucosal microbiota reveals universal microbial signatures and dysbiosis in gastric carcinogenesis. Oncogene 41 (28) (2022)
Xiansong Wang, Wei Hu, XiangChun Li, Dan Huang, Qing Li, Hung Chan, Judeng Zeng, Chuan Xie, Huarong Chen, Xiaodong Liu, Tony Gin, Maggie Haitian Wang, Alfred Sze Lok Cheng, Wei Kang, Ka-Fai To, Dariusz Plewczyński, Qingpeng Zhang, Xiaoting Chen, Danny Cheuk Wing Chan, Ho Ko, Sunny-Hei Wong, Jun Yu, Matthew Tak Vai Chan, Lin Zhang, William Ka Kei Wu
Single-Hit Inactivation Drove Tumor Suppressor Genes Out of the X Chromosome during Evolution. Cancer research 82 (8) (2022)
Yun Qian, Lianxin Zhou, Simson Tsz Yat Luk, Jiaying Xu, Weilin Li, Hongyan Gou, Huarong Chen, Wei Kang, Jun Yu, Chi Chun Wong
The sodium channel subunit SCNN1B suppresses colorectal cancer via suppression of active c-Raf and MAPK signaling cascade. Oncogene (2022)
Yun Qian, Lianxin Zhou, Simson Tsz Yat Luk, Jiaying Xu, Weilin Li, Hongyan Gou, Huarong Chen, Wei Kang, Jun Yu, Chi Chun Wong
The sodium channel subunit SCNN1B suppresses colorectal cancer via suppression of active c-Raf and MAPK signaling cascade. Oncogene 42 (8) (2022)
Xiaohong Wang, Lianhai Zhang, Jessie Qiaoyi Liang, Chi Chun Wong, Huarong Chen, Hongyan Gou, Yujuan Dong, Weixin Liu, Ziyu Li, Jia Fu Ji, Jun Yu
DUSP5P1 promotes gastric cancer metastasis and platinum drug resistance. Oncogenesis 11 (1) (2022)
Feiyu Shi, Gaixia Liu, Yufeng Lin, Cosmos Liutao Guo, Jing Han, Eagle S H Chu, Chengxin Shi, Yaguang Li, Haowei Zhang, Chenhao Hu, Ruihan Liu, Shui-Xiang He, Gang Guo, Yinnan Chen, Xiang Zhang, Olabisi Oluwabukola Coker, Sunny Hei Wong, Jun Yu, Junjun She
Altered gut microbiome composition by appendectomy contributes to colorectal cancer. Oncogene 42 (7) (2022)
Feiyu Shi, Gaixia Liu, Yufeng Lin, Cosmos Liutao Guo, Jing Han, Eagle S H Chu, Chengxin Shi, Yaguang Li, Haowei Zhang, Chenhao Hu, Ruihan Liu, Shui-Xiang He, Gang Guo, Yinnan Chen, Xiang Zhang, Olabisi Oluwabukola Coker, Sunny Hei Wong, Jun Yu, Junjun She
Altered gut microbiome composition by appendectomy contributes to colorectal cancer. Oncogene (2022)
Danyu Chen, Henley Cheung, Harry Cheuk Hay Lau, Jun Yu, Chi Chun Wong
N 6 -Methyladenosine RNA-Binding Protein YTHDF1 in Gastrointestinal Cancers: Function, Molecular Mechanism and Clinical Implication. Cancers 14 (14) (2022)
Yun Qian, Lianxin Zhou, Simson Tsz Yat Luk, Jiaying Xu, Weilin Li, Hongyan Gou, Huarong Chen, Wei Kang, Jun Yu, Chi Chun Wong
The sodium channel subunit SCNN1B suppresses colorectal cancer via suppression of active c-Raf and MAPK signaling cascade. Oncogene (2022)
Shubin Hong, Yubin Xie, Zhen Cheng, Jie Li, Weiman He, Zhuming Guo, Quan Zhang, Sui Peng, Minghui He, Shuang Yu, Lixia Xu, Rengyun Liu, Tianyi Xu, Yunjian Zhang, Yanbing Li, Ji-Guang Wang, Weiming Lv, Jun Yu, Hai-Peng Xiao
Distinct molecular subtypes of papillary thyroid carcinoma and gene signature with diagnostic capability. Oncogene 41 (47) (2022)
Yun Qian, Lianxin Zhou, Simson Tsz Yat Luk, Jiaying Xu, Weilin Li, Hongyan Gou, Huarong Chen, Wei Kang, Jun Yu, Chi Chun Wong
The sodium channel subunit SCNN1B suppresses colorectal cancer via suppression of active c-Raf and MAPK signaling cascade. Oncogene 42 (8) (2022)
Xiaoli Liu, Yifei Wang, Bonan Chen, Wai Nok Chan, Chun Wai Mui, Alvin H K Cheung, Jinglin Zhang, Kit Yee Wong, Jun Yu, Wei Kang, Ka Fai To
Targeting the Hippo Pathway in Gastric Cancer and Other Malignancies in the Digestive System: From Bench to Bedside. Biomedicines 10 (10) (2022)
Yun Qian, Lianxin Zhou, Simson Tsz Yat Luk, Jiaying Xu, Weilin Li, Hongyan Gou, Huarong Chen, Wei Kang, Jun Yu, Chi Chun Wong
The sodium channel subunit SCNN1B suppresses colorectal cancer via suppression of active c-Raf and MAPK signaling cascade. Oncogene 42 (8) (2022)
Yi Zhao, Xiaoxue Ren, Jing Lu, Minghui He, Zhe Liu, Lina Yi, Mingle Huang, Ming Kuang, Haipeng Xiao, Joseph Jao Yiu Sung, Xiao-Xing Li, Lixia Xu, Jun Yu
Mechanistic insight of SARS-CoV-2 infection using human hepatobiliary organoids. Gut (2022)
Yun Qian, Lianxin Zhou, Simson Tsz Yat Luk, Jiaying Xu, Weilin Li, Hongyan Gou, Huarong Chen, Wei Kang, Jun Yu, Chi Chun Wong
The sodium channel subunit SCNN1B suppresses colorectal cancer via suppression of active c-Raf and MAPK signaling cascade. Oncogene 42 (8) (2022)
Yu Shi, Guoping Wang, Harry Cheuk Hay Lau, Jun Yu
Metagenomic Sequencing for Microbial DNA in Human Samples: Emerging Technological Advances. International journal of molecular sciences 23 (4) (2022)
Yun Qian, Lianxin Zhou, Simson Tsz Yat Luk, Jiaying Xu, Weilin Li, Hongyan Gou, Huarong Chen, Wei Kang, Jun Yu, Chi Chun Wong
The sodium channel subunit SCNN1B suppresses colorectal cancer via suppression of active c-Raf and MAPK signaling cascade. Oncogene (2022)
Feiyu Shi, Gaixia Liu, Yufeng Lin, Cosmos Liutao Guo, Jing Han, Eagle S H Chu, Chengxin Shi, Yaguang Li, Haowei Zhang, Chenhao Hu, Ruihan Liu, Shui-Xiang He, Gang Guo, Yinnan Chen, Xiang Zhang, Olabisi Oluwabukola Coker, Sunny Hei Wong, Jun Yu, Junjun She
Altered gut microbiome composition by appendectomy contributes to colorectal cancer. Oncogene 42 (7) (2022)
Jinglin Zhang, Bonan Chen, Hui Li, Yifei Wang, Xiaoli Liu, Kit Yee Wong, Wai Nok Chan, Aden Ka Yin Chan, Alvin H K Cheung, Kam Tong Leung, Yujuan Dong, Yi Pan, Huixing Ke, Li Liang, Zhaocai Zhou, Jianyong Xiao, Chi Chun Wong, William K K Wu, Alfred S L Cheng, Brigette B Y Ma, Jun Yu, Kwok-Wai Lo, Wei Kang, Ka Fai To
Cancer-associated fibroblasts potentiate colorectal cancer progression by crosstalk of the IGF2-IGF1R and Hippo-YAP1 signaling pathways. The Journal of pathology (2022)
Asa Sergei Fong, Yasi Pan, Jun Yu, Chi Chun Wong
Interplay between the m 6 A Epitranscriptome and Tumor Metabolism: Mechanisms and Therapeutic Implications. Biomedicines 10 (10) (2022)
Feiyu Shi, Gaixia Liu, Yufeng Lin, Cosmos Liutao Guo, Jing Han, Eagle S H Chu, Chengxin Shi, Yaguang Li, Haowei Zhang, Chenhao Hu, Ruihan Liu, Shui-Xiang He, Gang Guo, Yinnan Chen, Xiang Zhang, Olabisi Oluwabukola Coker, Sunny Hei Wong, Jun Yu, Junjun She
Altered gut microbiome composition by appendectomy contributes to colorectal cancer. Oncogene 42 (7) (2022)
Xiaowu Bai, Hong Wei, Weixin Liu, Olabisi Oluwabukola Coker, Hongyan Gou, Changan Liu, Liuyang Zhao, Chuangen Li, Yunfei Zhou, Guoping Wang, Wei Kang, Enders Kwok-Wai Ng, Jun Yu
Cigarette smoke promotes colorectal cancer through modulation of gut microbiota and related metabolites. Gut 71 (12) (2022)
Gina Louise Trakman, Winnie Y Y Lin, Amy L Hamilton, Amy L Wilson-O'Brien, Annalise Stanley, Jessica Y Ching, Jun Yu, Joyce W Y Mak, Yang Sun, Junkun Niu, Yinglei Miao, Xiaoqing Lin, Rui Feng, Minhu Chen, Nitin Shivappa, James R Hébert, Mark Morrision, Siew C Ng, Michael A Kamm
Processed Food as a Risk Factor for the Development and Perpetuation of Crohn's Disease-The ENIGMA Study. Nutrients 14 (17) (2022)
Liuyang Zhao, Xiang Zhang, Yunfei Zhou, Kaili Fu, Harry Cheuk Hay Lau, Tommy Wai-Yiu Chun, Alvin Ho-Kwan Cheung, Olabisi Oluwabukola Coker, Hong Wei, William Ka-Kei Wu, Sunny Hei Wong, Joseph Jao-Yiu Sung, Ka-Fai To, Jun Yu
Parvimonas micra promotes colorectal tumorigenesis and is associated with prognosis of colorectal cancer patients. Oncogene 41 (36) (2022)
Feiyu Shi, Gaixia Liu, Yufeng Lin, Cosmos Liutao Guo, Jing Han, Eagle S H Chu, Chengxin Shi, Yaguang Li, Haowei Zhang, Chenhao Hu, Ruihan Liu, Shui-Xiang He, Gang Guo, Yinnan Chen, Xiang Zhang, Olabisi Oluwabukola Coker, Sunny Hei Wong, Jun Yu, Junjun She
Altered gut microbiome composition by appendectomy contributes to colorectal cancer. Oncogene 42 (7) (2022)
Chuangen Li, Yong Wang, Dabin Liu, Chi Chun Wong, Olabisi Oluwabukola Coker, Xiang Zhang, Changan Liu, Yunfei Zhou, Yali Liu, Wei Kang, Ka Fai To, Joseph Jao Yiu Sung, Jun Yu
Squalene epoxidase drives cancer cell proliferation and promotes gut dysbiosis to accelerate colorectal carcinogenesis. Gut 71 (11) (2022)
Dan Huang, Xiansong Wang, Ziheng Huang, Yingzhi Liu, Xiaodong Liu, Tony Gin, Sunny-Hei Wong, Jun Yu, Lin Zhang, Matthew Tak Vai Chan, Huarong Chen, William Ka Kei Wu
3'untranslated regions of tumor suppressor genes evolved specific features to favor cancer resistance. Oncogene 41 (23) (2022)
Shuang Yu, Changan Liu, Yingtong Hou, Jie Li, Zhuming Guo, Xinwen Chen, Luyao Zhang, Sui Peng, Shubin Hong, Lixia Xu, Xiaoxing Li, Rengyun Liu, Shuwei Chen, Bin Li, Zongpeng Weng, Yanbing Li, Weiming Lv, Jun Yu, Hai-Peng Xiao
Integrative metabolomic characterization identifies plasma metabolomic signature in the diagnosis of papillary thyroid cancer. Oncogene 41 (17) (2022)
Feiyu Shi, Gaixia Liu, Yufeng Lin, Cosmos Liutao Guo, Jing Han, Eagle S H Chu, Chengxin Shi, Yaguang Li, Haowei Zhang, Chenhao Hu, Ruihan Liu, Shui-Xiang He, Gang Guo, Yinnan Chen, Xiang Zhang, Olabisi Oluwabukola Coker, Sunny Hei Wong, Jun Yu, Junjun She
Altered gut microbiome composition by appendectomy contributes to colorectal cancer. Oncogene 42 (7) (2022)
Feiyu Shi, Gaixia Liu, Yufeng Lin, Cosmos Liutao Guo, Jing Han, Eagle S H Chu, Chengxin Shi, Yaguang Li, Haowei Zhang, Chenhao Hu, Ruihan Liu, Shui-Xiang He, Gang Guo, Yinnan Chen, Xiang Zhang, Olabisi Oluwabukola Coker, Sunny Hei Wong, Jun Yu, Junjun She
Altered gut microbiome composition by appendectomy contributes to colorectal cancer. Oncogene (2022)
Etienne Ho Kit Mok, Carmen Oi Ning Leung, Lei Zhou, Martina Mang Leng Lei, Hoi Wing Leung, Man Tong, Tin-Lok Wong, Eunice Yuen Ting Lau, Irene Oi Lin Ng, Jin Ding, Jing-Ping Yun, Jun Yu, Hui Lian Zhu, Chi Ho Lin, Dan Lindholm, Kit Sum Leung, Jonathan D Cybulski, David M Baker, Stephianie Ma, Terence Kin-Wah Lee
Caspase-3-Induced Activation of SREBP2 Drives Drug Resistance via Promotion of Cholesterol Biosynthesis in Hepatocellular Carcinoma. Cancer research 82 (17) (2022)
Xiaohong Wang, Lianhai Zhang, Francis K L Chan, Jia Fu Ji, Jun Yu, Jessie Qiaoyi Liang
Gamma-glutamyltransferase 7 suppresses gastric cancer by cooperating with RAB7 to induce mitophagy. Oncogene 41 (26) (2022)
Nick Lung-Ngai Ting, Harry Cheuk Hay Lau, Jun Yu
Cancer pharmacomicrobiomics: targeting microbiota to optimise cancer therapy outcomes. Gut 71 (7) (2022)
Shanshan Gao, Fraser Soares, Shiyan Wang, Chi Chun Wong, Huarong Chen, Zhenjie Yang, Weixin Liu, Minnie Y Y Go, Musaddeque Ahmed, Yong Zeng, Catherine Adell O'Brien, Joseph J Y Sung, Housheng Hansen He, Jun Yu
CRISPR screens identify cholesterol biosynthesis as a therapeutic target on stemness and drug resistance of colon cancer. Oncogene 40 (48) (2021)
Xi Kang, Weilin Li, Weixin Liu, Han Liang, Jingyu Deng, Chi Chun Wong, Sinan Zhao, Wei Kang, Ka-Fai To, Philip Wai-Yan Chiu, Guiying Wang, Jun Yu, Enders Kwok Wai Ng
LIMK1 promotes peritoneal metastasis of gastric cancer and is a therapeutic target. Oncogene 40 (19) (2021)
Rui Li, Qunxiang Ong, Chi Chun Wong, Eagle S H Chu, Joseph Jao Yiu Sung, Xiaoyong Yang, Jun Yu
O-GlcNAcylation inhibits hepatic stellate cell activation. Journal of gastroenterology and hepatology (2021)
Naoki Sugimura, Qing Li, Eagle Siu Hong Chu, Harry Cheuk Hay Lau, Winnie Fong, Weixin Liu, Cong Liang, Geicho Nakatsu, Anthony Chin Yang Su, Olabisi Oluwabukola Coker, William Ka Kei Wu, Francis Ka Leung Chan, Jun Yu
Lactobacillus gallinarum modulates the gut microbiota and produces anti-cancer metabolites to protect against colorectal tumourigenesis. Gut (2021)
Hui Xu, Chi Chun Wong, Weilin Li, Yunfei Zhou, Yan Li, Lifu Wang, Lei Liu, Jun Yu
RING-finger protein 6 promotes colorectal tumorigenesis by transcriptionally activating SF3B2. Oncogene 40 (47) (2021)
Jinkai Liu, Wei Geng, Hanyong Sun, Changan Liu, Fan Huang, Jie Cao, Lei Xia, Hongchuan Zhao, Jianning Zhai, Qing Li, Xiang Zhang, Ming Kuang, Shunli Shen, Qiang Xia, Vincent Wai-Sun Wong, Jun Yu
Integrative metabolomic characterisation identifies altered portal vein serum metabolome contributing to human hepatocellular carcinoma. Gut (2021)
Wei Kang, Jinglin Zhang, Tingting Huang, Yuhang Zhou, Chi Chun Wong, Ronald C K Chan, Yujuan Dong, Feng Wu, Bin Zhang, William Ka Kei Wu, Michael Wing-Yan Chan, Alfred S L Cheng, Jun Yu, Nathalie Wong, Kwok-Wai Lo, Ka-Fai To
NOTCH3, a crucial target of miR-491-5p/miR-875-5p, promotes gastric carcinogenesis by upregulating PHLDB2 expression and activating Akt pathway. Oncogene 40 (9) (2021)
Henley Cheung, Jun Yu
Machine learning on microbiome research in gastrointestinal cancer. Journal of gastroenterology and hepatology 36 (4) (2021)
Yufeng Lin, Guoping Wang, Jun Yu, Joseph Jao Yiu Sung
Artificial intelligence and metagenomics in intestinal diseases. Journal of gastroenterology and hepatology 36 (4) (2021)
Yiyun Chen, Wing Yin Cheng, Hongyu Shi, Shengshuo Huang, Huarong Chen, Dabin Liu, Weiqi Xu, Jun Yu, Ji-Guang Wang
Classifying gastric cancer using FLORA reveals clinically relevant molecular subtypes and highlights LINC01614 as a biomarker for patient prognosis. Oncogene 40 (16) (2021)
Wenxiu Liu, Hongyan Gou, Xiaohong Wang, Xiaoming Li, Xiaoxu Hu, Hao Su, Shengmian Li, Jun Yu
TTPAL promotes gastric tumorigenesis by directly targeting NNMT to activate PI3K/AKT signaling. Oncogene 40 (49) (2021)
Shiyan Wang, Chi Chun Wong, Yanquan Zhang, Junzhe Huang, Chuangen Li, Jianning Zhai, Guoping Wang, Hong Wei, Xueji Zhang, Housheng Hansen He, Jun Yu
ZNF545 loss promotes ribosome biogenesis and protein translation to initiate colorectal tumorigenesis in mice. Oncogene 40 (48) (2021)
Jun Wen, Harry Cheuk Hay Lau, Maikel Petrus Peppelenbosch, Jun Yu
Gastric Microbiota beyond H. pylori: An Emerging Critical Character in Gastric Carcinogenesis. Biomedicines 9 (11) (2021)
Jingwan Zhang, Jianning Zhai, Chi Chun Wong, Huarong Chen, Xiaohong Wang, Jia Fu Ji, Jun Yu
A novel amplification gene PCI domain containing 2 (PCID2) promotes colorectal cancer through directly degrading a tumor suppressor promyelocytic leukemia (PML). Oncogene 40 (49) (2021)
Hui Xu, Lei Liu, Weilin Li, Duowu Zou, Jun Yu, Lifu Wang, Chi Chun Wong
Transcription factors in colorectal cancer: molecular mechanism and therapeutic implications. Oncogene 40 (9) (2020)
Xiang Zhang, Olabisi Oluwabukola Coker, Eagle Sh Chu, Kaili Fu, Harry Cheuk Hay Lau, Yi-Xiang Wang, Anthony W H Chan, Hong Wei, Xiaoyong Yang, Joseph J Y Sung, Jun Yu
Dietary cholesterol drives fatty liver-associated liver cancer by modulating gut microbiota and metabolites. Gut 70 (4) (2020)
Winnie Fong, Qing Li, Jun Yu
Gut microbiota modulation: a novel strategy for prevention and treatment of colorectal cancer. Oncogene 39 (26) (2020)
Harry Cheuk Hay Lau, Jun Yu
Gut microbiome alters functions of mutant p53 to promote tumorigenesis. Signal transduction and targeted therapy 5 (1) (2020)
Xiaoxuan Xia, William Ka Kei Wu, Sunny Hei Wong, Dabin Liu, Thomas Ngai Yeung Kwong, Geicho Nakatsu, Pearlly S Yan, Yu-Ming Chuang, Michael Wing-Yan Chan, Olabisi Oluwabukola Coker, Zigui Chen, Yun Kit Yeoh, Liuyang Zhao, Xiansong Wang, Wing Yin Cheng, Matthew Tak Vai Chan, Paul Kay Sheung Chan, Joseph Jao Yiu Sung, Maggie Haitian Wang, Jun Yu
Bacteria pathogens drive host colonic epithelial cell promoter hypermethylation of tumor suppressor genes in colorectal cancer. Microbiome 8 (1) (2020)
Qinyao Wei, Yun Qian, Jun Yu, Chi Chun Wong
Metabolic rewiring in the promotion of cancer metastasis: mechanisms and therapeutic implications. Oncogene 39 (39) (2020)
Jinglin Zhang, Chi Chun Wong, Kam-Tong Leung, Feng Wu, Yuhang Zhou, Joanna Hung-Man Tong, Ronald C K Chan, Hui Li, Yifei Wang, Huan Yan, Liping Liu, William Ka Kei Wu, Michael Wing-Yan Chan, Alfred S L Cheng, Jun Yu, Nathalie Wong, Kwok-Wai Lo, Ka-Fai To, Wei Kang
FGF18-FGFR2 signaling triggers the activation of c-Jun-YAP1 axis to promote carcinogenesis in a subgroup of gastric cancer patients and indicates translational potential. Oncogene 39 (43) (2020)
Feixue Wang, Jennie Ka Ching Lau, Jun Yu
The role of natural killer cell in gastrointestinal cancer: killer or helper. Oncogene 40 (4) (2020)
Wing Yin Cheng, Chun-Ying Wu, Jun Yu
The role of gut microbiota in cancer treatment: friend or foe? Gut 69 (10) (2020)
Xiaohang Long, Chi Chun Wong, Li Tong, Eagle S H Chu, Chun Ho Szeto, Minne Y Y Go, Olabisi Oluwabukola Coker, Anthony W H Chan, Francis K L Chan, Joseph J Y Sung, Jun Yu
Peptostreptococcus anaerobius promotes colorectal carcinogenesis and modulates tumour immunity. Nature microbiology 4 (12) (2019)
Juqiang Han, Xiang Zhang, Jennie K-C Lau, Kaili Fu, Harry Ch Lau, Weiqi Xu, Eagle Sh Chu, Hui Yao Lan, Jun Yu
Bone marrow-derived macrophage contributes to fibrosing steatohepatitis through activating hepatic stellate cells. The Journal of pathology 248 (4) (2019)
Dabin Liu, Chi Chun Wong, Li Fu, Huarong Chen, Liuyang Zhao, Chuangen Li, Yunfei Zhou, Yanquan Zhang, Weiqi Xu, Yidong Yang, Bin Wu, Gong Cheng, Paul Bo-San Lai, Nathalie Wong, Joseph J Y Sung, Jun Yu
Squalene epoxidase drives NAFLD-induced hepatocellular carcinoma and is a pharmaceutical target. Science translational medicine 10 (437) (2019)
En-Wei Tao, Wing Yin Cheng, Wei-Lin Li, Jun Yu, Qin-Yan Gao
tiRNAs: A novel class of small noncoding RNAs that helps cells respond to stressors and plays roles in cancer progression. Journal of cellular physiology 235 (2) (2019)
Lin Zhang, William K K Wu, Richard L Gallo, Evandro F Fang, Wei Hu, Thomas K W Ling, Jing Shen, Ruby L Y Chan, Lan Lu, Xiao M Luo, Mingxing Li, Kam M Chan, Jun Yu, Vincent Wai-Sun Wong, Siew C Ng, Sunny-Hei Wong, Francis Ka Leung Chan, Joseph J Y Sung, Matthew Tak Vai Chan, Chi H Cho
Critical Role of Antimicrobial Peptide Cathelicidin for Controlling Helicobacter pylori Survival and Infection. Journal of immunology (Baltimore, Md. : 1950) 196 (4) (2016)

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Jun Yu