Super-resolution visualization and modeling of human chromosomal regions reveals cohesin-dependent loop structures.

Xian HaoJyotsana J ParmarBenoît LelandaisAndrey AristovWei OuyangChristian WeberChristophe Zimmer

Published in: Genome biology (2021)

Our results provide new constraints on chromatin structure and showcase an affordable non-invasive approach to study genome organization in single cells.

Keyphrases

induced apoptosis
endothelial cells
transcription factor
genome wide
gene expression
cell cycle arrest
dna damage
high resolution
copy number
induced pluripotent stem cells
endoplasmic reticulum stress
pluripotent stem cells
mass spectrometry