Wilms tumor treatment protocol compliance and the influence on outcomes for children in Tanzania.
Austin WesevichGeorge MochaFrank KiwaraColin ChaoIdd ShabaniJohn Z IgengeKristin M SchroederPublished in: Pediatric blood & cancer (2023)
Nonadherence with recommended Wilms tumor treatment guidelines due to key health system delays correlated to reduced overall survival rates, with chemotherapy nonadherence due to abandonment, lack of surgery, and deaths on therapy as the strongest contributors. Future interventions targeting health system delays and reducing deaths during therapy are critical to improving protocol compliance and increasing overall survival for pediatric Wilms tumor patients in low-resource settings.
Keyphrases
- randomized controlled trial
- ejection fraction
- newly diagnosed
- minimally invasive
- young adults
- squamous cell carcinoma
- metabolic syndrome
- mesenchymal stem cells
- combination therapy
- atrial fibrillation
- current status
- cancer therapy
- locally advanced
- coronary artery disease
- weight loss
- rectal cancer
- percutaneous coronary intervention
- glycemic control
- smoking cessation
- surgical site infection