A randomized double-blind placebo-controlled trial of the effectiveness of melatonin on neurocognition and sleep in survivors of childhood cancer.
Margaret M LubasBelinda N MandrellWilliam L GreeneCarrie R HowellRobbin ChristensenCara I KimbergChenghong LiKristen K NessDeo Kumar SrivastavaMelissa M HudsonLeslie L RobisonKevin R KrullTara M BrinkmanPublished in: Pediatric blood & cancer (2021)
Melatonin was not associated with improved neurocognitive performance or sleep in our intent-to-treat analyses; however, a subset of survivors demonstrated a clinically significant treatment response.