Not just "leuko" after all: Epithelial leukotriene production in type 2 immunity.

Published in: Science immunology (2022)

New research shows that specialized epithelial cells (tuft cells) are major producers of lipid mediators (leukotrienes) that drive allergic inflammation and host defense against helminth parasites. (See the related Research Article by Ualiyeva et al .).

Keyphrases

induced apoptosis
oxidative stress
cell cycle arrest
endoplasmic reticulum stress
fatty acid
cell death
signaling pathway
innate immune