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Effects of endocrine disruptors on fetal testis development, male puberty, and transition age.

Francesco CargneluttiAndrea Di NisioFrancesco PallottiIva SabovicMatteo SpazianiMaria Grazia TarsitanoDonatella PaoliCarlo Foresta
Published in: Endocrine (2020)
We conclude that current evidence does not clarify the impact of EDs on human male reproductive health, although severe harmful effects had been reported in animals. Despite controversial results, overall conclusion points toward a positive association between exposure to EDs and reproductive system damage. Further long-term studies performed on wide number of subjects are necessary in order to identify damaging compounds and remove them from the environment.
Keyphrases
  • endothelial cells
  • oxidative stress
  • induced pluripotent stem cells
  • pluripotent stem cells
  • case control
  • drug induced