Two-drug antiretroviral regimens: an assessment of virologic response and durability among treatment-experienced persons living with HIV in the OPERA® Observational Database.
Gerald PieroneCassidy HenegarJennifer S FuscoVani VannappagariMichael AboudLeigh RagoneGregory P FuscoPublished in: Journal of the International AIDS Society (2020)
In this large cohort of treatment-experienced patients, 2-DR prescriptions were common and more frequent among patients with significant comorbidity. Virologic response was similar, but duration of use was shorter with a 2-DR than a 3-DR, suggesting that 2-DRs may be a virologically effective treatment strategy for treatment-experienced PLHIV with existing comorbidities.