PD-L1 regulates tumor proliferation and T-cell function in NF2-associated meningiomas.
Ying WangChao ZhangMinjun YanXin MaLairong SongBo WangPeng LiPi-Nan LiuPublished in: CNS neuroscience & therapeutics (2024)
Targeting PD-L1 could be helpful for restoring the function of tumor-infiltrating lymphocytes and inducing apoptosis to inhibit tumor proliferation in NF2-associated meningiomas. Dissecting the mechanisms of the PD-L1-driven tumorigenesis of NF2-associated meningioma will help to improve our understanding of the mechanisms underlying tumor progression and could facilitate further refinement of current therapies to improve the treatment of NF2 patients.