Novel Peptides from Sea Cucumber Intestinal Enzyme Hydrolysates Promote Osteogenic Differentiation of Bone Mesenchymal Stem Cells via Phosphorylation of PPARγ at Serine 112.
Hao YueZhibing LengYuying BoYingying TianZiyi YanChanghu XuePing DongJingfeng WangPublished in: Molecular nutrition & food research (2023)
Supplement with SCIP promoted BMSCs to differentiate into osteoblasts. These results suggested that SCIP had potential as a functional food to improve obesity and osteoporosis. This article is protected by copyright. All rights reserved.
Keyphrases
- bone mineral density
- mesenchymal stem cells
- insulin resistance
- protein kinase
- postmenopausal women
- human health
- metabolic syndrome
- umbilical cord
- weight loss
- high fat diet induced
- type diabetes
- body composition
- weight gain
- bone marrow
- adipose tissue
- risk assessment
- skeletal muscle
- bone loss
- cell therapy
- amino acid
- stem cells
- climate change