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ABCG2-Expressing Clonal Repopulating Endothelial Cells Serve to Form and Maintain Blood Vessels.

Yang LinChang-Hyun GilKimihiko BannoMasataka YokoyamaMatthew WingoEllen GoNutan PrasainYing LiuTakashi HatoHisamichi NaitoTaku WakabayashiMusia SominskaiaMeng GaoKevin ChenFuqiang GengJesus Maria Gomez SalineroSisi ChenW Christopher ShelleyMomoko YoshimotoSergio Li CalziMichael P MurphyKyoji HorieMaria B GrantRyan SchreinerDavid RedmondDavid P BasileShahin RafiiMervin C Yoder
Published in: Circulation (2024)
These results are the first to establish that a single prospective marker identifies CRECs in mice and human individuals, which holds promise to provide new cell therapies for repair of damaged vessels in patients with endothelial dysfunction.
Keyphrases
  • endothelial cells
  • high glucose
  • single cell
  • genome wide
  • vascular endothelial growth factor
  • cell therapy
  • high fat diet induced
  • type diabetes
  • big data
  • wild type
  • stem cells
  • pluripotent stem cells