Radioactivity Reduction of 2-Deoxy-2-[18F] Fluoro-D-Glucose by Milk and Ursodeoxycholic Acid in Preclinical Study.
Hwan-Jeong JeongTarique Rajasaheb BagalkotHyeon Soo KimYeon-Hee HanMinjoo KimSeok Tae LimMyung-Hee SohnPublished in: Nuclear medicine and molecular imaging (2020)
The present study demonstrated that administration of milk and UDCA increased G6Pase expression levels and 18F-FDG release from the tissue. These results suggest milk and UDCA could be used to reduce radiation exposure from 18F-FDG after image acquisition. The mechanisms underpinning this phenomenon should be explored in a human study.