18F-labeled anti-human CD20 cys-diabody for same-day immunoPET in a model of aggressive B cell lymphoma in human CD20 transgenic mice.
Kirstin A ZettlitzRichard TavaréWen-Ting K TsaiReiko E YamadaNoel S HaJeffrey CollinsR Michael van DamJohn M TimmermanAnna M WuPublished in: European journal of nuclear medicine and molecular imaging (2018)
[18F]FB-GAcDb and [18F]FBEM-GAcDb could monitor normal B cells and B cell malignancies non-invasively and quantitatively in vivo. In contrast to [18F]FDG PET, immunoPET provides not only information about the extent of disease but also about presence and localisation of the therapeutic target.