Clinical features and immunogenetic risk factors associated with additional autoantibodies in anti-transcriptional intermediary factor 1γ juvenile-onset dermatomyositis.
Matthew A ShermanQingyuan YangLaura Gutierrez-AlamilloKatherine PakWilly Albert FlegelAndrew Lee MammenLisa G RiderLivia A Casciola-Rosennull nullPublished in: Arthritis & rheumatology (Hoboken, N.J.) (2023)
Autoantibodies associated with anti-TIF1γ were found in isolation and in combination among a subset of patients with JDM. Patients with these autoantibodies had less severe muscle disease and were not enriched for HLA-DRB1*03. Additional autoantibodies among anti-TIF1γ-positive patients with JDM likely contribute to the heterogeneity of the anti-TIF1γ serologic subgroup. This article is protected by copyright. All rights reserved.