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PD-L1 expression and infiltration by CD4+ and FoxP3+ T cells are increased in Xp11 translocation renal cell carcinoma and indicate poor prognosis.

Hyun Jung LeeDong Hoon ShinYeon J LeeSo J LeeChung S HwangAhrong KimWon Y ParkJung H LeeKyung U ChoiJee Y KimChang H LeeMee Y SolSung W Park
Published in: Histopathology (2020)
PD-L1 expression was higher in TRCC than in other types of RCC. High PD-L1 tumour cell expression and tumour infiltration by CD4+ and FoxP3+ immune cells were associated with poor RFS in TRCC.
Keyphrases
  • poor prognosis
  • renal cell carcinoma
  • long non coding rna
  • regulatory t cells
  • single cell
  • cell therapy
  • dendritic cells
  • immune response
  • bone marrow