Comparison of Perioperative Pregabalin and Duloxetine for Pain Management After Total Knee Arthroplasty: A Double-Blind Clinical Trial.

Farnad Imani Azadeh Emami Mahzad Alimian Nasim Nikoubakht Niloofar Khosravi Mehdi Rajabi Arthur Christopher Hertling

Published in: Anesthesiology and pain medicine (2023)

Perioperative oral pregabalin and duloxetine similarly reduce pain and the need for analgesic consumption within 48 hours after TKA but do not affect knee mobility status.

Keyphrases

pain management
neuropathic pain
total knee arthroplasty
clinical trial
chronic pain
cardiac surgery
patients undergoing
spinal cord
spinal cord injury
postoperative pain
knee osteoarthritis
study protocol
phase ii
acute kidney injury
randomized controlled trial
phase iii
clinical evaluation