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Increased Colonic Expression of ACE2 Associates with Poor Prognosis in Crohn's disease.

Takahiko ToyonagaKenza C ArabaMeaghan M KennedyBenjamin P KeithElisabeth A WolberCaroline BeasleyErin C SteinbachMatthew R SchanerAnimesh JainMillie D LongEdward L BarnesHans H HerfarthKim L IsaacsJonathan J HansenMuneera KapadiaJosé Gaston GuillemMark J KorudaReza RahbarTim SadiqAjay S GulatiPraveen SethupathyTerrence S FureyCamille EhreShehzad Z Sheikh
Published in: bioRxiv : the preprint server for biology (2020)
Increased intestinal expression of ACE2 is associated with deteriorated clinical outcomes in CD patients. These data point to the need for molecular stratification that may impact CD disease-related outcomes.
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