Increased Colonic Expression of ACE2 Associates with Poor Prognosis in Crohn's disease.

Takahiko ToyonagaKenza C ArabaMeaghan M KennedyBenjamin P KeithElisabeth A WolberCaroline BeasleyErin C SteinbachMatthew R SchanerAnimesh JainMillie D LongEdward L BarnesHans H HerfarthKim L IsaacsJonathan J HansenMuneera KapadiaJosé Gaston GuillemMark J KorudaReza RahbarTim SadiqAjay S GulatiPraveen SethupathyTerrence S FureyCamille EhreShehzad Z Sheikh

Published in: bioRxiv : the preprint server for biology (2020)

Increased intestinal expression of ACE2 is associated with deteriorated clinical outcomes in CD patients. These data point to the need for molecular stratification that may impact CD disease-related outcomes.

Keyphrases

poor prognosis
long non coding rna
end stage renal disease
ejection fraction
newly diagnosed
angiotensin ii
angiotensin converting enzyme
prognostic factors
peritoneal dialysis
binding protein
metabolic syndrome
adipose tissue
skeletal muscle
deep learning
artificial intelligence
weight loss
glycemic control