Factors associated with liver injury and prognosis in advanced cancer patients treated with immune checkpoint inhibitors.

Shun KanekoYasuhiro AsahinaMina NakagawaMiyako MurakawaYasunari MiyazakiTakahiro AsakageShohei FukudaTakeshi NamikiYoshito KanoMasashi NagataJun TsuchiyaMasato MiyoshiFukiko Kitahata-KawaiSayuri NittaYasuhiro ItsuiSei KakinumaRyuichi Okamoto

Published in: Hepatology research : the official journal of the Japan Society of Hepatology (2023)

The incidence of irLI was significantly higher in patients treated with anti-CTLA-4 agents. Even in patients with preexisting grade 1 AST/ALT elevation, appropriate follow-up, and control of the irLI can improve prognosis. This article is protected by copyright. All rights reserved.

Keyphrases

liver injury
advanced cancer
drug induced
palliative care
risk factors