Citrullinated histone H3 expression in anti-neutrophil cytoplasmic antibody-associated vasculitis in older Japanese autopsy patients.

Yoko MatsudaMitsuyo ItabashiYasuko TachibanaTakahiko SugiharaYasuhiro SakashitaTomoyasu MatsubaraShigeo MurayamaWako YumuraAkira ShimizuTakashi TakeiTomio Arai

Published in: Geriatrics & gerontology international (2019)

We report severe clinicopathological characteristics of AAV in older patients. Expression of citH3 was a useful marker to evaluate vasculitis severity. Identification of these features might aid in the diagnosis of AAV. Geriatr Gerontol Int 2019; 19: 259-264.

Keyphrases

poor prognosis
end stage renal disease
ejection fraction
chronic kidney disease
newly diagnosed
prognostic factors
gene therapy
binding protein
patient reported outcomes
middle aged
community dwelling