Association of Myocardial Changes and Gene Expression of the NFATC1 and NFATC4 -Calcineurin Signaling Pathway in Children with Bicuspid Aortic Valve.
Andrii KamenshchykMargaryta GoncharValentyn OksenychAleksandr KamyshnyiPublished in: Children (Basel, Switzerland) (2023)
In children with BAV the high expression of the NFATC1 calcineurin signaling pathway gene is associated with elevated PWTd and Ao.
Keyphrases
- aortic valve
- signaling pathway
- gene expression
- aortic stenosis
- transcatheter aortic valve replacement
- young adults
- aortic valve replacement
- transcatheter aortic valve implantation
- pi k akt
- poor prognosis
- epithelial mesenchymal transition
- left ventricular
- dna methylation
- induced apoptosis
- genome wide
- heart failure
- copy number
- binding protein
- ejection fraction
- coronary artery disease
- endoplasmic reticulum stress
- long non coding rna
- atrial fibrillation