Long-term efficacy, safety, and tolerability, including behavior and executive functioning, during adjunctive lacosamide treatment in pediatric patients with uncontrolled epilepsy.
Mark Kristof FarkasIryna MakedonskaCynthia BellerDimitrios BourikasChristine de la LogeSvetlana DimovaFlorin FloricelCarrie McClungBrian MoseleySheila TherriaultJesus Eric Pina-GarzaPublished in: Epilepsy & behavior : E&B (2024)
In this analysis of a large patient pool from 2 open-label trials, long-term adjunctive LCM was efficacious and generally well tolerated in children with epilepsy and focal-onset or generalized seizures. Behavior and executive functioning were generally stable without observable worsening during long-term adjunctive LCM treatment.