Circulating Tumor DNA Analysis Guiding Adjuvant Therapy in Stage II Colon Cancer.
Jeanne TieJoshua D CohenKamel LahouelSerigne N LoYuxuan WangSuzanne KosmiderRachel WongJeremy ShapiroMargaret LeeSam HarrisAdnan KhattakMatthew BurgeMarion HarrisJames LynamLouise NottFiona DayTheresa HayesSue-Anne McLachlanBelinda LeeJanine PtakNatalie SillimanLisa DobbynMaria PopoliRalph HrubanAnne Marie LennonNicholas PapadopoulosKenneth W KinzlerBert VogelsteinCristian TomasettiPeter Gibbsnull nullPublished in: The New England journal of medicine (2022)
A ctDNA-guided approach to the treatment of stage II colon cancer reduced adjuvant chemotherapy use without compromising recurrence-free survival. (Supported by the Australian National Health and Medical Research Council and others; DYNAMIC Australian New Zealand Clinical Trials Registry number, ACTRN12615000381583.).