Effect of red wine or its polyphenols on induced apical periodontitis in rats.

Renan Dal-Fabbro Leopoldo Cosme-SilvaFernanda Rezende Silva Martins de OliveiraLetícia Cabrera CapalboFlávia Alfredo PlazzaEdilson ErvolinoLuciano Tavares Angelo Cintra João Eduardo Gomes-Filho

Published in: International endodontic journal (2021)

Red wine administration to rats for 15 days before induction of apical periodontitis decreased inflammation, TRAP marking and periapical bone resorption compared to alcohol. Resveratrol-quercetin administration reduced the inflammatory process in apical periodontitis, periapical bone resorption, and altered the OPG, IL-10 and TRAP expression compared to C and ALC groups.

Keyphrases

bone loss
oxidative stress
bone mineral density
poor prognosis
diabetic rats
soft tissue
high glucose
bone regeneration
cone beam computed tomography
postmenopausal women
body composition
cone beam