PD-L1 and IDO1 expression and tumor-infiltrating lymphocytes in osteosarcoma patients: comparative study of primary and metastatic lesions.
Yu TodaKenichi KohashiYuichi YamadaMasato YoshimotoShin IshiharaYoshihiro ItoTakeshi IwasakiHidetaka YamamotoYoshihiro MatsumotoYasuharu NakashimaMasaaki MawatariYoshinao OdaPublished in: Journal of cancer research and clinical oncology (2020)
Our results suggest that the PD-L1 and IDO1 immune checkpoint inhibitors may provide clinical benefit in osteosarcoma patients with metastatic lesions after conventional chemotherapy.