Microsurgical Reconstruction of the Jaws Using Vascularised Free Flap Technique in Patients with Medication-Related Osteonecrosis: A Systematic Review.

Roberto SaccoNicola SaccoUmar HamidSyed Hasan AliMark SinghJohn St J Blythe

Published in: BioMed research international (2018)

Based on the limited data available in literature (Level 4 of the Oxford Evidence-based medicine scale), micro-osseous-vascular reconstruction of the jaws represents a valid treatment in patients with bisphosphonate-related osteonecrosis at stage III of the disease. However, additional data based on a larger cohort of patients are necessary to justify this type of intervention in patient affected by MRONJ.

Keyphrases

end stage renal disease
electronic health record
randomized controlled trial
ejection fraction
newly diagnosed
chronic kidney disease
systematic review
big data
peritoneal dialysis
case report
patient reported outcomes
combination therapy
drug induced
middle cerebral artery
breast reconstruction