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Association of maternal circulating 25(OH)D and calcium with birth weight: A mendelian randomisation analysis.

William David ThompsonJessica TyrrellMaria-Carolina BorgesRobin N BeaumontBridget A KnightAndrew R WoodSusan M RingAndrew T HattersleyRachel M FreathyDeborah A Lawlor
Published in: PLoS medicine (2019)
Our results suggest that maternal circulating 25(OH)D does not influence birth weight in otherwise healthy newborns. However, the effect of maternal circulating calcium on birth weight is unclear and requires further exploration with more research including RCT and/or MR analyses with more valid instruments.
Keyphrases
  • birth weight
  • gestational age
  • weight gain
  • preterm birth
  • body mass index
  • pregnant women
  • magnetic resonance imaging
  • preterm infants
  • contrast enhanced
  • data analysis