Jessica Tyrrell (Jess S Tyrrell, Jess Tyrrell)

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 34

Top Topics

Body Mass Index

Physical Activity

Cross Sectional

Top Venues

Nature communications

International journal of epidemiology

This page only lists publications with an associated author ORCID identifier.

Publications

Pavel Loginovic, Feiyi Wang, Jiang Li, Lauric A Ferrat, Uyenlinh L Mirshahi, H Shanker Rao, Axel Petzold, Jessica Tyrrell, Harry D Green, Michael N Weedon, Andrea Ganna, Tiinamaija Tuomi, David J Carey, null null, null null, null null, Richard D Oram, Tasanee Braithwaite
Applying a genetic risk score model to enhance prediction of future multiple sclerosis diagnosis at first presentation with optic neuritis. Nature communications 15 (1) (2024)
Harry D Green, Ella Burden, Ji Chen, Jonathan Evans, Kashyap Patel, Andrew R Wood, Robin N Beaumont, Jessica Tyrrell, Timothy M Frayling, Andrew T Hattersley, Richard A Oram, Jack Bowden, Inês A Barroso, Christopher Smith, Michael N Weedon
Hyperglycaemia is a causal risk factor for upper limb pathologies. International journal of epidemiology 53 (1) (2024)
Bethan Mallabar-Rimmer, Samuel William David Merriel, Amy P Webster, Leigh Jackson, Andrew R Wood, Matthew Barclay, Jessica Tyrrell, Katherine S Ruth, Christina Thirlwell, Richard Oram, Michael N Weedon, Sarah E R Bailey, Harry D Green
Colorectal cancer risk stratification using a polygenic risk score in symptomatic primary care patients-a UK Biobank retrospective cohort study. European journal of human genetics : EJHG (2024)
Pavel Loginovic, Feiyi Wang, Jiang Li, Lauric A Ferrat, Uyenlinh L Mirshahi, H Shanker Rao, Axel Petzold, Jessica Tyrrell, Harry D Green, Michael N Weedon, Andrea Ganna, Tiinamaija Tuomi, David J Carey, null null, null null, null null, Richard D Oram, Tasanee Braithwaite
Applying a genetic risk score model to enhance prediction of future multiple sclerosis diagnosis at first presentation with optic neuritis. Nature communications 15 (1) (2024)
Grace Marion Power, Naomi Warne, Helen Bould, Francesco Casanova, Samuel E Jones, Tom G Richardson, Jessica Tyrrell, George Davey Smith, Jon Heron
The role of body image dissatisfaction in the relationship between body size and disordered eating and self-harm: complimentary Mendelian randomization and mediation analyses. Molecular psychiatry (2024)
Harry D Green, Ella Burden, Ji Chen, Jonathan Evans, Kashyap Patel, Andrew R Wood, Robin N Beaumont, Jessica Tyrrell, Timothy M Frayling, Andrew T Hattersley, Richard A Oram, Jack Bowden, Inês A Barroso, Christopher Smith, Michael N Weedon
Hyperglycaemia is a causal risk factor for upper limb pathologies. International journal of epidemiology (2024)
Pavel Loginovic, Feiyi Wang, Jiang Li, Lauric A Ferrat, Uyenlinh L Mirshahi, H Shanker Rao, Axel Petzold, Jessica Tyrrell, Harry D Green, Michael N Weedon, Andrea Ganna, Tiinamaija Tuomi, David J Carey, null null, null null, null null, Richard D Oram, Tasanee Braithwaite
Applying a genetic risk score model to enhance prediction of future multiple sclerosis diagnosis at first presentation with optic neuritis. Nature communications 15 (1) (2024)
Jessica O'Loughlin, Francesco Casanova, Amanda M Hughes, Zammy Fairhurst-Hunter, Liming Li, Zhengming Chen, null null, Jack Bowden, Ed Watkins, Rachel M Freathy, Laura D Howe, Robin G Walters, Jessica Tyrrell
BMI and well-being in people of East Asian and European ancestry: a Mendelian randomisation study. Translational psychiatry 13 (1) (2023)
Francesco Casanova, Jessica O'Loughlin, Vasilis Karageorgiou, Robin N Beaumont, Jack Bowden, Andrew R Wood, Jessica Tyrrell
Effects of physical activity and sedentary time on depression, anxiety and well-being: a bidirectional Mendelian randomisation study. BMC medicine 21 (1) (2023)
Gareth Hawkes, Loic Yengo, Sailaja Vedantam, Eirini Marouli, Robin N Beaumont, null null, Jessica Tyrrell, Michael N Weedon, Joel Hirschhorn, Timothy M Frayling, Andrew R Wood
Identification and analysis of individuals who deviate from their genetically-predicted phenotype. PLoS genetics 19 (9) (2023)
Francesco Casanova, Jessica O'Loughlin, Vasilis Karageorgiou, Robin N Beaumont, Jack Bowden, Andrew R Wood, Jessica Tyrrell
Effects of physical activity and sedentary time on depression, anxiety and well-being: a bidirectional Mendelian randomisation study. BMC medicine 21 (1) (2023)
Francesco Casanova, Jessica O'Loughlin, Vasilis Karageorgiou, Robin N Beaumont, Jack Bowden, Andrew R Wood, Jessica Tyrrell
Effects of physical activity and sedentary time on depression, anxiety and well-being: a bidirectional Mendelian randomisation study. BMC medicine 21 (1) (2023)
Francesco Casanova, Jessica O'Loughlin, Vasilis Karageorgiou, Robin N Beaumont, Jack Bowden, Andrew R Wood, Jessica Tyrrell
Effects of physical activity and sedentary time on depression, anxiety and well-being: a bidirectional Mendelian randomisation study. BMC medicine 21 (1) (2023)
Charli E Harlow, Vickas V Patel, Dawn M Waterworth, Andrew R Wood, Robin N Beaumont, Katherine S Ruth, Jessica Tyrrell, Asami Oguro-Ando, Audrey Y Chu, Timothy M Frayling
Genetically proxied therapeutic prolyl-hydroxylase inhibition and cardiovascular risk. Human molecular genetics (2022)
Mark Gilchrist, Francesco Casanova, Jessica Tyrrell, Stuart Cannon, Andrew R Wood, Nicole Fife, Katherine G Young, Richard A Oram, Michael N Weedon
Prevalence of Fabry disease-causing variants in the UK Biobank. Journal of medical genetics (2022)
William David Thompson, Robin N Beaumont, Alan Kuang, Nicole M Warrington, Yingjie Ji, Jessica Tyrrell, Andrew R Wood, Denise M Scholtens, Bridget A Knight, David M Evans, William L Lowe, Gillian Santorelli, Raq Azad, Dan Mason, Andrew T Hattersley, Timothy M Frayling, Hanieh Yaghootkar, Maria Carolina Borges, Deborah A Lawlor, Rachel M Freathy
Fetal alleles predisposing to metabolically favorable adiposity are associated with higher birth weight. Human molecular genetics 31 (11) (2022)
Francesco Casanova, Jessica O'Loughlin, Cathryn Lewis, Timothy M Frayling, Andrew R Wood, Jessica Tyrrell
Simulated distributions from negative experiments highlight the importance of the body mass index distribution in explaining depression-body mass index genetic risk score interactions. International journal of epidemiology 51 (5) (2022)
Michael N Weedon, Samuel E Jones, Jacqueline M Lane, Jiwon Lee, Hanna M Ollila, Amy Dawes, Jessica Tyrrell, Robin N Beaumont, Timo Partonen, Ilona Merikanto, Stephen S Rich, Jerome I Rotter, Timothy M Frayling, Martin K Rutter, Susan Redline, Tamar Sofer, Richa Saxena, Andrew R Wood
The impact of Mendelian sleep and circadian genetic variants in a population setting. PLoS genetics 18 (9) (2022)
William David Thompson, Robin N Beaumont, Alan Kuang, Nicole M Warrington, Yingjie Ji, Jessica Tyrrell, Andrew R Wood, Denise M Scholtens, Bridget A Knight, David M Evans, William L Lowe, Gillian Santorelli, Rafaq Azad, Dan Mason, Andrew T Hattersley, Timothy M Frayling, Hanieh Yaghootkar, Maria-Carolina Borges, Deborah A Lawlor, Rachel M Freathy
Higher maternal adiposity reduces offspring birthweight if associated with a metabolically favourable profile. Diabetologia 64 (12) (2021)
Jessica O'Loughlin, Francesco Casanova, Samuel E Jones, Saskia P Hagenaars, Robin N Beaumont, Rachel M Freathy, Edward R Watkins, Céline Vetter, Martin K Rutter, Sean W Cain, Andrew J K Phillips, Daniel P Windred, Andrew R Wood, Michael N Weedon, Jessica Tyrrell
Using Mendelian Randomisation methods to understand whether diurnal preference is causally related to mental health. Molecular psychiatry (2021)
Emma L Anderson, Rebecca C Richmond, Samuel E Jones, Gibran Hemani, Kaitlin H Wade, Hassan S Dashti, Jacqueline M Lane, Heming Wang, Richa Saxena, Ben Brumpton, Roxanna Korologou-Linden, Jonas B Nielsen, Bjørn Olav Åsvold, Gonçalo Abecasis, Elizabeth Coulthard, Simon D Kyle, Robin N Beaumont, Jessica Tyrrell, Timothy M Frayling, Marcus R Munafò, Andrew R Wood, Yoav Ben-Shlomo, Laura D Howe, Deborah A Lawlor, Michael N Weedon, George Davey Smith
Is disrupted sleep a risk factor for Alzheimer's disease? Evidence from a two-sample Mendelian randomization analysis. International journal of epidemiology 50 (3) (2021)
Harry D Green, Alistair Jones, Jonathan Peter Evans, Andrew R Wood, Robin N Beaumont, Jessica Tyrrell, Timothy M Frayling, Christopher Smith, Michael N Weedon
A genome-wide association study identifies 5 loci associated with frozen shoulder and implicates diabetes as a causal risk factor. PLoS genetics 17 (6) (2021)
Mark Gormley, James Yarmolinsky, Tom Dudding, Kimberley Burrows, Richard M Martin, Steven Thomas, Jessica Tyrrell, Paul J Brennan, Miranda Pring, Stefania Boccia, Andrew F Olshan, Brenda Diergaarde, Rayjean J Hung, Geoffrey Liu, Danny Nigel Legge, Eloiza H Tajara, Patricia Severino, Martin Lacko, Andrew R Ness, George Davey Smith, Emma E Vincent, Rebecca C Richmond
Using genetic variants to evaluate the causal effect of cholesterol lowering on head and neck cancer risk: A Mendelian randomization study. PLoS genetics 17 (4) (2021)
Grace Marion Power, Jessica Tyrrell, Timothy M Frayling, George Davey Smith, Tom G Richardson
Mendelian Randomization Analyses Suggest Childhood Body Size Indirectly Influences End Points From Across the Cardiovascular Disease Spectrum Through Adult Body Size. Journal of the American Heart Association 10 (17) (2021)
Jessica Tyrrell, Jie Zheng, Robin Beaumont, Kathryn Hinton, Tom G Richardson, Andrew R Wood, George Davey Smith, Timothy M Frayling, Kate Tilling
Genetic predictors of participation in optional components of UK Biobank. Nature communications 12 (1) (2021)
Mark Gormley, Tom Dudding, Eleanor C M Sanderson, Richard M Martin, Steven Thomas, Jessica Tyrrell, Andrew R Ness, Paul J Brennan, Marcus R Munafo, Miranda Pring, Stefania Boccia, Andrew F Olshan, Brenda Diergaarde, Rayjean J Hung, Geoffrey Liu, George Davey Smith, Rebecca C Richmond
A multivariable Mendelian randomization analysis investigating smoking and alcohol consumption in oral and oropharyngeal cancer. Nature communications 11 (1) (2020)
Francesco Casanova, Andrew R Wood, Hanieh Yaghootkar, Robert N Beaumont, Samuel E Jones, Kim M Gooding, Kunihiko Aizawa, William David Strain, Andrew T Hattersley, Faisel Khan, Angela C Shore, Timothy M Frayling, Jessica Tyrrell
A Mendelian Randomization Study Provides Evidence That Adiposity and Dyslipidemia Lead to Lower Urinary Albumin-to-Creatinine Ratio, a Marker of Microvascular Function. Diabetes 69 (5) (2020)
William David Thompson, Jessica Tyrrell, Maria-Carolina Borges, Robin N Beaumont, Bridget A Knight, Andrew R Wood, Susan M Ring, Andrew T Hattersley, Rachel M Freathy, Deborah A Lawlor
Association of maternal circulating 25(OH)D and calcium with birth weight: A mendelian randomisation analysis. PLoS medicine 16 (6) (2019)
Samuel E Jones, Vincent Theodoor van Hees, Diego R Mazzotti, Pedro-Manuel Marques-Vidal, Séverine Sabia, Ashley van der Spek, Hassan S Dashti, Jorgen Engmann, Desana Kocevska, Jessica Tyrrell, Robin N Beaumont, Melvyn Hillsdon, Katherine S Ruth, Marcus A Tuke, Hanieh Yaghootkar, Seth A Sharp, Yingjie Ji, James W Harrison, Rachel M Freathy, Anna Murray, Annemarie I Luik, Najaf Amin, Jacqueline M Lane, Richa Saxena, Martin K Rutter, Henning Tiemeier, Zoltán Kutalik, Meena Kumari, Timothy M Frayling, Michael N Weedon, Philip R Gehrman, Andrew R Wood
Genetic studies of accelerometer-based sleep measures yield new insights into human sleep behaviour. Nature communications 10 (1) (2019)
Jessica Tyrrell, Cheryl Paterson, Alison Curnow
Regression Analysis of Protoporphyrin IX Measurements Obtained During Dermatological Photodynamic Therapy. Cancers 11 (1) (2019)
Ashley Budu-Aggrey, Ben Brumpton, Jessica Tyrrell, Sarah Holmes Watkins, Ellen H Modalsli, Carlos A Celis-Morales, Lyn D Ferguson, Gunnhild Åberge Vie, Tom M Palmer, Lars G Fritsche, Mari Løset, Jonas Bille Nielsen, Wei Zhou, Lam C Tsoi, Andrew R Wood, Samuel E Jones, Robin N Beaumont, Marit Saunes, Pål Richard Romundstad, Stefan Siebert, Iain B McInnes, James T Elder, George Davey Smith, Timothy M Frayling, Bjørn Olav Åsvold, Sara J Brown, Naveed Sattar, Lavinia Paternoster
Evidence of a causal relationship between body mass index and psoriasis: A mendelian randomization study. PLoS medicine 16 (1) (2019)
Heming Wang, Jacqueline M Lane, Samuel E Jones, Hassan S Dashti, Hanna M Ollila, Andrew R Wood, Vincent Theodoor van Hees, Ben Michael Brumpton, Bendik Slagsvold Winsvold, Katri Kantojärvi, Teemu Palviainen, Brian E Cade, Tamar Sofer, Yanwei Song, Krunal Patel, Simon George Anderson, David A Bechtold, Jack Bowden, Richard Emsley, Simon D Kyle, Max A Little, Andrew S Loudon, Frank A J L Scheer, Shaun M Purcell, Rebecca C Richmond, Kai Spiegelhalder, Jessica Tyrrell, Xiaofeng Zhu, Christer Hublin, Jaakko A Kaprio, Kati Kristiansson, Sonja Sulkava, Tiina Paunio, Kristian Hveem, Jonas B Nielsen, Cristen J Willer, John-Anker Zwart, Linn B Strand, Timothy M Frayling, David Ray, Deborah A Lawlor, Martin K Rutter, Michael N Weedon, Susan Redline, Richa Saxena
Genome-wide association analysis of self-reported daytime sleepiness identifies 42 loci that suggest biological subtypes. Nature communications 10 (1) (2019)
Hassan S Dashti, Samuel E Jones, Andrew R Wood, Jacqueline M Lane, Vincent Theodoor van Hees, Heming Wang, Jessica A Rhodes, Yanwei Song, Krunal Patel, Simon George Anderson, Robin N Beaumont, David A Bechtold, Jack Bowden, Brian E Cade, Marta Garaulet, Simon D Kyle, Max A Little, Andrew S Loudon, Annemarie I Luik, Frank A J L Scheer, Kai Spiegelhalder, Jessica Tyrrell, Daniel J Gottlieb, Henning Tiemeier, David W Ray, Shaun M Purcell, Timothy M Frayling, Susan Redline, Deborah A Lawlor, Martin K Rutter, Michael N Weedon, Richa Saxena
Genome-wide association study identifies genetic loci for self-reported habitual sleep duration supported by accelerometer-derived estimates. Nature communications 10 (1) (2019)
Luke C Pilling, Janice C Atkins, Michael O Duff, Robin N Beaumont, Samuel E Jones, Jessica Tyrrell, Chia-Ling Kuo, Katherine S Ruth, Marcus A Tuke, Hanieh Yaghootkar, Andrew R Wood, Anna Murray, Michael N Weedon, Lorna W Harries, George A Kuchel, Luigi Ferrucci, Timothy M Frayling, David Melzer
Red blood cell distribution width: Genetic evidence for aging pathways in 116,666 volunteers. PloS one 12 (9) (2017)