Fascin protein stabilization by miR-146a implicated in the process of a chronic inflammation-related colon carcinogenesis model.

Yusuke KandaTokuichi KawaguchiMitsuhiko OsakiKunishige OnumaTakahiro OchiyaTomoyuki KitagawaFutoshi Okada

Published in: Inflammation research : official journal of the European Histamine Research Society ... [et al.] (2018)

We found that stable fascin expression is brought about via the inhibition of proteasome degradation by miR-146a in the process of a chronic inflammation-related colon carcinogenesis.

Keyphrases

cell proliferation
long non coding rna
oxidative stress
poor prognosis
long noncoding rna
binding protein