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Protocol for the RETHINK study: a randomised, double-blind, parallel-group, non-inferiority clinical trial comparing acetaminophen and NSAIDs for treatment of chronic pain in elderly patients with osteoarthritis of the hip and knee.

Makoto EndoShinya KawaharaTaishi SatoMasami TokunagaToshihiko HaraTaro MawatariTsutomu KawanoSadamoto ZendaTempei MiyajiMototsugu ShimokawaSanae SakamotoToshio TakanoMasumi MiyakeHiroyuki AonoYasuharu Nakashimanull null
Published in: BMJ open (2023)
jRCTs071200112.
Keyphrases
  • clinical trial
  • double blind
  • chronic pain
  • placebo controlled
  • study protocol
  • open label
  • phase ii
  • phase iii
  • randomized controlled trial
  • pain management
  • knee osteoarthritis
  • middle aged
  • combination therapy
  • liver injury