Effects of Environmental pH on the Growth of Gastric Cancer Cells.
Wenjie LiYing ZhouChunyu ShangHui SangHong ZhuPublished in: Gastroenterology research and practice (2020)
Compared with the microacid environment, the microalkaline environment inhibited the viability, invasion, and expression of genes and proteins (mTOR, AKT, Wnt, Glut, and HIF-1α) but promoted the apoptosis of GC cells and thus inhibited the growth of GC.α) at pH 6, pH 7, and pH 8.
Keyphrases
- cell cycle arrest
- cell proliferation
- induced apoptosis
- endoplasmic reticulum stress
- oxidative stress
- stem cells
- poor prognosis
- cell death
- signaling pathway
- genome wide
- endothelial cells
- gene expression
- pi k akt
- dna methylation
- cell migration
- gas chromatography
- climate change
- simultaneous determination
- genome wide identification
- life cycle