A likelihood ratio test for changes in homeolog expression bias.

Ronald D SmithTaliesin J KinserGregory D Conradi SmithJoshua R Puzey

Published in: BMC bioinformatics (2019)

The likelihood ratio test derived here is a direct, transparent, and easily implemented method for detecting changes in homeolog expression bias that outperforms alternative approaches. While our method was derived with homeolog analysis in mind, this method can be used to analyze changes in the ratio of expression levels between any two genes in any two conditions.

Keyphrases

poor prognosis
binding protein
long non coding rna
gene expression
genome wide
dna methylation
transcription factor
data analysis
bioinformatics analysis