Two new alkaloids isolated from Dictamnus dasycarpus Turcz.
Sun YeYan LiuSi-Yi WangMing-Yuan GuoJia-Tong WuZhi-Chao HaoJuan PanWei GuanHai-Xue KuangBing-You YangPublished in: Natural product research (2024)
Two new quinoline alkaloids ( 1 - 2 ) together with twenty-two known alkaloids ( 3 - 24 ) were isolated and identified from Dictamnus dasycarpus Turcz. Compounds 6 - 7 , 9 , 11 , 15 - 16 , 19 and 24 were isolated from D. dasycarpus for the first time. The structures of all compounds were characterised by spectroscopic methods (1D, 2D NMR and HRESIMS). The anti-proliferative activity was mediated by the arrest of three human cancer cell lines (SW982, HepG2 and A549) of all the compounds that were evaluated by CCK-8 assay.