Quantitative versus standard pupillary light reflex for early prognostication in comatose cardiac arrest patients: an international prospective multicenter double-blinded study.

Mauro OddoClaudio SandroniGiuseppe CiterioJohn-Paul MirozJanneke HornMalin RundgrenAlain CariouJean-François PayenChristian StormPascal StammetFabio Silvio Taccone

Published in: Intensive care medicine (2018)

Quantitative NPi had excellent ability to predict an unfavorable outcome from day 1 after CA, with no false positives, and significantly higher specificity than standard manual pupillary examination. The addition of NPi to SSEP increased sensitivity of outcome prediction, while maintaining 100% specificity.

Keyphrases

cardiac arrest
end stage renal disease
cardiopulmonary resuscitation
ejection fraction
chronic kidney disease
newly diagnosed
high resolution
peritoneal dialysis
cross sectional
structural basis
protein kinase