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Genome-wide gene by environment study of time spent in daylight and chronotype identifies emerging genetic architecture underlying light sensitivity.

Angus C BurnsAndrew J K PhillipsMartin K RutterRicha SaxenaSean W CainJacqueline M Lane
Published in: Sleep (2022)
This study is the first to assess light as an important exposure in the genomics of chronotype and is a critical first step in uncovering the genetic architecture of human circadian light sensitivity and its links to sleep and mental health.
Keyphrases
  • genome wide
  • mental health
  • copy number
  • endothelial cells
  • sleep quality
  • induced pluripotent stem cells
  • pluripotent stem cells