Central obesity is selectively associated with cerebral gray matter atrophy in 15,634 subjects in the UK Biobank.
Chris-Patrick PflanzDaniel J TozerEric L HarshfieldJonathan TayDavid R FitzPatrickHugh S MarkusPublished in: International journal of obesity (2005) (2022)
Central body-fat distribution rather than the overall body-fat percentage is associated with gray matter changes in people with obesity. Further work is required to identify the factors that mediate the association between central obesity and GM atrophy.