Central obesity is selectively associated with cerebral gray matter atrophy in 15,634 subjects in the UK Biobank.

Chris-Patrick PflanzDaniel J Tozer Eric L HarshfieldJonathan TayDavid R FitzPatrickHugh S Markus

Published in: International journal of obesity (2005) (2022)

Central body-fat distribution rather than the overall body-fat percentage is associated with gray matter changes in people with obesity. Further work is required to identify the factors that mediate the association between central obesity and GM atrophy.

Keyphrases

insulin resistance
metabolic syndrome
weight loss
high fat diet induced
type diabetes
weight gain
adipose tissue
subarachnoid hemorrhage
skeletal muscle
body mass index
cross sectional