Detection of glioblastoma intratumor heterogeneity in radiosensitivity using patient-derived neurosphere cultures.

Joseph H McAbeeCharlotte Degorre-KerbaulKristin ValdezAstrid WendlerUma T ShankavaramColin WattsKevin CamphausenPhilip J Tofilon

Published in: Journal of neuro-oncology (2020)

Data suggest a tumor dependent ITH in radiosensitivity. The existence of ITH in radiosensitivity may impact not only the initial therapeutic response but also the effectiveness of retreatment protocols.

Keyphrases

randomized controlled trial
systematic review
electronic health record
single cell
big data
real time pcr
machine learning
artificial intelligence
deep learning