Do Protocadherins Show Prognostic Value in the Carcinogenesis of Human Malignant Neoplasms? Systematic Review and Meta-Analysis.
Thâmara Manoela Marinho BezerraThâmara Manoela Marinho BezerraEalber Carvalho Macêdo LunaFrancisco Samuel Rodrigues CarvalhoFilipe Nobre ChavesPaulo Goberlânio de Barros SilvaFábio Wildson Gurgel CostaKaruza Maria Alves PereiraPublished in: Asian Pacific journal of cancer prevention : APJCP (2020)
In this systematic review, we have demonstrated using meta-analysis that PCDHs could emerge as potential tumor suppressor genes and that a significant increase in methylation may be useful for early detection of different cancers. This work may help in the identification of new prognostic biomarkers in malignant neoplasms.