MATRIN3 deficiency triggers autoinflammation via cGAS-STING activation.

Zohirul IslamAhsan PolashMasataka SuzawaBryan ChimSkyler KuhnSabrina SultanaNicholas CutronaPatrick T SmithJuraj KabatSundar GanesanAmir ForoushaniMarkus Hafner Stefan A Muljo

Published in: bioRxiv : the preprint server for biology (2024)

) in the absence of MATR3 unleashes R-loops and interferon-stimulated genes.

Keyphrases

genome wide
dendritic cells
genome wide identification
bioinformatics analysis
replacement therapy
gene expression
dna methylation
transcription factor