Minimal ablative margin (MAM) assessment with image fusion: an independent predictor for local tumor progression in hepatocellular carcinoma after stereotactic radiofrequency ablation.

Gregor LaimerPeter SchullianNikolai JaschkeDaniel PutzerGernot EberleAmilcar AlzagaBruno OdisioReto Bale

Published in: European radiology (2020)

• An intraoperatively measured minimal ablative margin (MAM) > 5 mm correlates with complete remission. • MAM is the only significant independent predictor of LTP (OR = 0.7, 95% CI 0.5-0.98, p = 0.036) after stereotactic RFA of hepatocellular carcinoma. • Image fusion using commercially available rigid imaging registration software is possible, even though considerably complex. Therefore, improved (semi-)automatic fusion software is highly desirable.

Keyphrases

radiofrequency ablation
deep learning
high resolution
brain metastases
poor prognosis
data analysis
small cell lung cancer
long non coding rna
mass spectrometry
clinical evaluation